The overall aim of NANCY is to introduce a secure and intelligent architecture for the beyond the fifthgeneration (B5G)wireless network. Leveraging AI and blockchain, NANCY enables secure andintelligent resource management, flexible networking, and orchestration.In this direction, novel architectures, namely point-to-point (P2P) connectivity for device-to-deviceconnectivity, mesh networking, and relay-based communications, as well as protocols for mediumaccess, mobility management, and resource allocation will be designed. These architectures andprotocols will make the most by jointly optimizing the midhaul, and fronthaul. This is expected toenable truly distributed intelligence and transform the network to a low-power computer. Likewise, byfollowing a holistic optimization approach and leveraging the developments in blockchain, NANCYaims at supporting E2E personalized, multi-tenant and perpetual protection.